MOLECULAR BIOLOGY AND GENETICS (MASTER) (WHIT THESIS)
Master	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Ders Genel Tanıtım Bilgileri

Course Code:

3015002021

Ders İsmi:

Transcriptome and Proteome

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
3	0	3	7

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Anabilim Dalı/Lisansüstü Seçmeli

Course Level:

Master

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:

Understanding the genome, genome sequencing, genome expression, biomedical genome and proteome reseach, protein 3D structure, protein function.

Course Content:

Defining Genomes, whole genome sequencing, conserved genes in diverse species, overview of human genome, can the genome alter gene expression without changing the DNA sequence ? genomic identifications; make new vaccines, new types of antibiotics, invent new types of medications using genomic sequences, genomic variations, genetically modified organisms, DNA microarrays, proteins for different conditions, structure and function of protein, protein chips

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Students will learn genome sequencing and genome expression.
2) Students will have detailed knowledge about biomedical genome and proteome reseach.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) Students will learn 3D structure of protein.
Field Specific Competence
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	Defining Genomes	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
2)	Whole genome sequencing	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
3)	Conserved genes in diverse species	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
4)	Overview of human genome	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
5)	Can the genome alter gene expression without changing the DNA sequence ?	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
6)	Genomic identifications	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
7)	Make new vaccines, new types of antibiotics, invent new types of medications using genomic sequences	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
8)	Midterm
9)	Make new vaccines, new types of antibiotics, invent new types of medications using genomic sequences	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
10)	Genomic variations	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
11)	Genetically modified organisms	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
12)	DNA microarrays	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
13)	Proteins for different conditions	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
14)	Structure and function of protein	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
15)	Recent Publication Discussion
16)	Final

Sources

Course Notes / Textbooks:	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)
References:	Discovering Genomics, Proteomics and Bioinformatics (2nd Edition) A. Malcolm Campbell, Laurie J. Heyer, Cold Spring Harbor Laboratory Press and Benjamin Cummings: (2006)

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	3	2
Program Outcomes
1) Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2) Use of advanced theoretical and practical knowledge within the field.
3) Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
4) Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field.
5) Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data.
6) Organize and implement project and activities for social environment with a sense of social responsibility.
7) Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level.
8) Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge.
9) Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach.
10) Determine learning needs and direct the learning.
11) Develop positive attitude towards lifelong learning.
12) Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field.
13) Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
14) Conduct studies at an advanced level in the field independently.
15) Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field.
16) Planning and managing activities towards the development of subordinates in the framework of a project.

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2)	Use of advanced theoretical and practical knowledge within the field.
3)	Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
4)	Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field.
5)	Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data.
6)	Organize and implement project and activities for social environment with a sense of social responsibility.
7)	Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level.
8)	Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge.
9)	Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach.
10)	Determine learning needs and direct the learning.
11)	Develop positive attitude towards lifelong learning.
12)	Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field.
13)	Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
14)	Conduct studies at an advanced level in the field independently.
15)	Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field.
16)	Planning and managing activities towards the development of subordinates in the framework of a project.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Akran Değerlendirmesi
Anlatım
Course
Grup çalışması ve ödevi

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Homework
Uygulama
Sunum

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	15	% 20
Midterms	1	% 30
Semester Final Exam	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	15	3	45
Study Hours Out of Class	15	5	75
Presentations / Seminar	5	2	10
Homework Assignments	15	2	30
Quizzes	15	2	30
Midterms	1	3	3
Final	1	3	3
Total Workload			196