MEDICAL LABORATORY TECHNIQUES
Associate	TR-NQF-HE: Level 5	QF-EHEA: Short Cycle	EQF-LLL: Level 5

Ders Genel Tanıtım Bilgileri

Course Code:

2020121002

Ders İsmi:

Medical Biology nad Genetic

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
2	0	2	5

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Necessary

Course Level:

Associate

TR-NQF-HE:5. Master`s Degree

QF-EHEA:Short Cycle

EQF-LLL:5. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi Hatice Nur HALİPÇİ TOPSAKAL

Course Lecturer(s):

Dr.Öğr.Üyesi Hilal ŞAHİN

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:

To have general information about biomolecules, cell structure and function, energy metabolism, quality of genetic material, DNA packaging and structure of chromosome, RNA structure synthesis and function, genetic code and protein synthesis, Mendelian genetics, cell cycle, mutation, gene engineering.

Course Content:

Structure of the Cell, Cell Membrane and Organelles, Cell Cycle, Mitosis and Meiosis, Cell Signal Transmission Mechanisms, Cell senescence,Cell senescence and apoptosis,DNA, RNA, Gene, Chromatin, Chromosome, Replication, Transcription and Translation Mechanisms, Gene Expression and Epigenetic Mechanisms, Mutation, Polymorphism Concepts and DNA Repair Mechanisms,Cancer and its Mechanism, Mendelian Genetics, Stem cell biology and treatments, Molecular genetic diseases and diagnostic methods. Human genome project are the content of the course.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Knows cell biology, cell structure, cell membrane and organelles.
2) Knows and distinguishes Cell Cycle, Mitosis and Meiosis.
3) List and explain Cell Signal Transmission Mechanisms.
4) Explain cellular senescence and apoptosis.
5) Makes the definitions of DNA, RNA, Gene, Chromatin, Chromosome.
6) Explain the Replication, Transcription and Translation Mechanisms
7) Knows Gene Expression and Epigenetic Mechanisms.
8) Midterm
9) Knows Mutation, Polymorphism Concepts and DNA Repair Mechanisms.
10) Explains cancer and its mechanism.
11) Knows Mendelian Genetics.
12) Knows stem cell biology and lists treatments.
13) Lists molecular genetic diseases and diagnostic methods.
14) Knows the human genome project.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	Cell Biology Introduction	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
2)	Structure of the Cell, Cell Membrane and Organelles,	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
3)	Cell Cycle, Mitosis and Meiosis,	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
4)	Cell Signal Transmission Mechanisms	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
5)	Cell senescence and apoptosis	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
6)	DNA, RNA, Gene, Chromatin, Chromosome,	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
7)	Replication, Transcription and Translation Mechanisms	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
8)	Midterm
9)	Gene Expression and Epigenetic Mechanisms	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
10)	Mutation, Polymorphism Concepts and DNA Repair Mechanisms	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
11)	Cancer and its Mechanism	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
12)	Mendelian Genetics	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
13)	Stem cell biology and treatments	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
14)	Molecular genetic diseases and diagnostic methods	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
15)	The human genome project is the content of the course.	1. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 2. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi., 3. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel.
16)	Final Exam

Sources

Course Notes / Textbooks:

Güneş, H.V. (2014). Moleküler Hücre Biyolojisi (Gözden geçirilmiş ikinci baskı). İstanbul: İstanbul Medikal Yayıncılık. 2. Başaran, A. (2010). Tıbbi Biyoloji Ders Kitabı. Ankara: Pelikan Yayınevi. 3. Kasap, H. (Ed.).(2010) Tıbbi Biyoloji ve Genetik. Adana: Nobel Kitabevi. 4. Karakaş, M. (2014) Moleküler Biyoloji. İstanbul: Nobel. 5. Afyon, A. (Ed.).(2015). Biyolojide Özel Konular. İstanbul: Nobel Akademik Yayıncılık.

References:

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Program Outcomes
1) Have basic knowledge about normal structure-functions of human systems.
2) Gains knowledge about the workflow and organization in medical laboratories.
3) Have basic theoretical and applied knowledge about the field.
4) Knows manual and automatic analysis methods in the Medical Laboratory and produces solutions in case of malfunctions.
5) Takes the samples that the specialist physician deems necessary from the patient in an appropriate way, and performs the sample transfer under appropriate conditions.
6) Performs routine examinations in the medical laboratory, follows the sample, concludes the analysis and establishes the relationship with the diseases.
7) Accurately obtains the findings, organizes them, presents them for sharing and use in accordance with the purpose.
8) Takes safety precautions in the medical laboratory, applies personal safety rules and creates a safe laboratory environment.
9) In the working environment; applies first aid and emergency care in accordance with the guide/directive in emergency situations.
10) Takes responsibility in a given task and carries it out individually and takes responsibility in working groups when necessary.
11) Gains proficiency in recognizing devices related to the field and fixing simple problems.
12) It carries out the necessary activities for the professional development of the employees under its responsibility.
13) Participates in the necessary programs, vocational in-service training activities and other studies in order to improve herself personally and professionally by updating the knowledge, skills and competencies related to her field with the awareness of lifelong learning.
14) It follows the developments in technology and science and has the consciousness of constantly renewing itself.
15) Gains the ability to communicate effectively with physicians ,colleagues, other healthcare professionals and patients in an ethical framework., other healthcare professionals and patients in an ethical framework.
16) Uses his/her mother tongue at a good level in oral and written communication for his/her profession.
17) He/she makes preliminary preparations for manual and automatic studies before analysis.
18) Applies basic tests related to different areas of the medical laboratory.
19) Uses medical laboratory equipment in accordance with its rules and techniques, ensures that they work in the most efficient way by controlling and maintaining them.
20) Have sufficient awareness of environmental protection and occupational safety.

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Have basic knowledge about normal structure-functions of human systems.
2)	Gains knowledge about the workflow and organization in medical laboratories.
3)	Have basic theoretical and applied knowledge about the field.
4)	Knows manual and automatic analysis methods in the Medical Laboratory and produces solutions in case of malfunctions.
5)	Takes the samples that the specialist physician deems necessary from the patient in an appropriate way, and performs the sample transfer under appropriate conditions.
6)	Performs routine examinations in the medical laboratory, follows the sample, concludes the analysis and establishes the relationship with the diseases.
7)	Accurately obtains the findings, organizes them, presents them for sharing and use in accordance with the purpose.
8)	Takes safety precautions in the medical laboratory, applies personal safety rules and creates a safe laboratory environment.
9)	In the working environment; applies first aid and emergency care in accordance with the guide/directive in emergency situations.
10)	Takes responsibility in a given task and carries it out individually and takes responsibility in working groups when necessary.
11)	Gains proficiency in recognizing devices related to the field and fixing simple problems.
12)	It carries out the necessary activities for the professional development of the employees under its responsibility.
13)	Participates in the necessary programs, vocational in-service training activities and other studies in order to improve herself personally and professionally by updating the knowledge, skills and competencies related to her field with the awareness of lifelong learning.
14)	It follows the developments in technology and science and has the consciousness of constantly renewing itself.
15)	Gains the ability to communicate effectively with physicians ,colleagues, other healthcare professionals and patients in an ethical framework., other healthcare professionals and patients in an ethical framework.
16)	Uses his/her mother tongue at a good level in oral and written communication for his/her profession.
17)	He/she makes preliminary preparations for manual and automatic studies before analysis.
18)	Applies basic tests related to different areas of the medical laboratory.
19)	Uses medical laboratory equipment in accordance with its rules and techniques, ensures that they work in the most efficient way by controlling and maintaining them.
20)	Have sufficient awareness of environmental protection and occupational safety.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Anlatım
Beyin fırtınası /Altı şapka
Course

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 40
Semester Final Exam	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	2	28
Study Hours Out of Class	14	5	70
Midterms	1	25	25
Final	1	25	25
Total Workload			148