MEDICINE
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Ders Genel Tanıtım Bilgileri

Course Code:

1010002090

Ders İsmi:

Stem Cell Techniques And Applicatıons In Medicine

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
2	0	2	2

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Bölüm Seçmeli

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Assoc. Prof. Özge ÜNLÜ

Course Lecturer(s):

Dr.Öğr.Üyesi Burcu BİLTEKİN

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:

To have knowledge about stem cell biology and plasticity. To learn main cell purification techniques, basic information and mechanisms.

Course Content:

Definitions of stem cells, proliferation of differentiated cells, hematopoietic stem cells, differentiated cell types, purification techniques and their use in medicine. Mesenchymal stem cells, differentiated cell types, purification techniques and their use in medicine. Stem cell biology and plasticity. Basic stem cell techniques [Immunomagnetic ( Magnetic), Immunodensity (Density-based) Methods, Positive selection, Negative selection] and aseptic conditions. Flow cytometry method and evaluation principles. Stem cell usage areas.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) Learns the definition, general properties and types of stem cells.
2) Learns the factors (markers) that determine the plasticity of stem cells. Learns the molecular mechanisms of cellular events that are effective in self-renewal, proliferation, differentiation, reprogramming and aging of stem cells.
3) Knows stem cell types, sources, properties and applications in regenerative medicine. Learns different types of specialized stem cell niches that host tissue/organ stem cells.
4) Learns laboratory techniques (isolation, characterization, differentiation and molecular techniques, microscopic analysis) used in stem cell studies. Learns the applications of stem cells in tissue engineering.
Field Specific Competence
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	Acquire basic information about cell culture	none
2)	Obtain basic information about cell lines	none
3)	Gain basic knowledge of cell culture techniques	none
4)	Acquire basic information about Primary Cell culture and passage	none
5)	Gain basic knowledge of freezing and thawing cells and cell lines	none
6)	Gains basic information about cell culture usage areas.	none
7)	Gains basic knowledge about the concept of stem cells	none
8)	Gain basic knowledge of stem cells life cycle, stress and aging	none
9)	Gain basic knowledge of pluripotent stem cells	none
10)	Gain basic knowledge of embryo and fetus derived multipotent stem cells	none
11)	Gain basic knowledge of adult stem cells	none
12)	Gains basic information about cancer stem cell	none

Sources

Course Notes / Textbooks:	Ders Kitapları
References:	Textbooks

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3	4
Program Outcomes
1) Explain the basic structure, development and normal functioning of the human body at the level of molecules, cells, tissues, organs and systems.
2) Questions the abnormal structure and functioning of the human body, explains it with information based on qualified scientific research, evaluates the causes of diseases by considering the interaction with the individual and his environment.
3) Evaluates clinical decision making and management processes of diseases under the guidance of evidence-based medicine practices.
4) Defines the concepts of health and disease in individual and social contexts, explains health seeking and health protection behaviors, national health service delivery and administrative processes.
5) Knows the research processes that form the basis of medical knowledge, has a level of foreign language knowledge to follow the developments in this field.
6) Takes medical history from the applicant/patient and their relatives.
7) Performs physical examination of individuals, evaluates diagnostic tests, manages diagnosis and treatment processes by using appropriate process steps.
8) Applies medical interventions to individuals for diagnosis, treatment or prevention.
9) Plans and realizes practices for the protection and improvement of health in individual and social dimensions.
10) Plans a scientific research, implements and evaluates the results.
11) Demonstrates lifelong learning behavior by making use of scientific and technological developments for professional and social changes.
12) Fulfills its responsibilities as a physician within the framework of professional values, ethical principles and legal regulations, regardless of language, religion, race, gender, social and cultural discrimination in the individual and society it serves.
13) He / she works in teams with his colleagues and other healthcare professionals in the processes of protecting and improving health in individual and social dimensions, and managing diseases.
14) Organizes and keeps records of health and disease related data obtained from individuals and society in medical and administrative contexts.
15) It strives to protect and develop the health of the individual and the society and to provide health services for the benefit of the individuals who make up the society.

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Explain the basic structure, development and normal functioning of the human body at the level of molecules, cells, tissues, organs and systems.
2)	Questions the abnormal structure and functioning of the human body, explains it with information based on qualified scientific research, evaluates the causes of diseases by considering the interaction with the individual and his environment.
3)	Evaluates clinical decision making and management processes of diseases under the guidance of evidence-based medicine practices.
4)	Defines the concepts of health and disease in individual and social contexts, explains health seeking and health protection behaviors, national health service delivery and administrative processes.
5)	Knows the research processes that form the basis of medical knowledge, has a level of foreign language knowledge to follow the developments in this field.
6)	Takes medical history from the applicant/patient and their relatives.
7)	Performs physical examination of individuals, evaluates diagnostic tests, manages diagnosis and treatment processes by using appropriate process steps.
8)	Applies medical interventions to individuals for diagnosis, treatment or prevention.
9)	Plans and realizes practices for the protection and improvement of health in individual and social dimensions.
10)	Plans a scientific research, implements and evaluates the results.
11)	Demonstrates lifelong learning behavior by making use of scientific and technological developments for professional and social changes.
12)	Fulfills its responsibilities as a physician within the framework of professional values, ethical principles and legal regulations, regardless of language, religion, race, gender, social and cultural discrimination in the individual and society it serves.
13)	He / she works in teams with his colleagues and other healthcare professionals in the processes of protecting and improving health in individual and social dimensions, and managing diseases.
14)	Organizes and keeps records of health and disease related data obtained from individuals and society in medical and administrative contexts.
15)	It strives to protect and develop the health of the individual and the society and to provide health services for the benefit of the individuals who make up the society.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Sözlü sınav
Homework

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 40
Semester Final Exam	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100