MOLECULAR BIOLOGY AND GENETICS (MASTER) (WHIT THESIS)
Qualification Awarded	Program Süresi	Toplam Kredi (AKTS)	Öğretim Şekli	Yeterliliğin Düzeyi ve Öğrenme Alanı
Master's ( Second Cycle) Degree	2	120	FULL TIME	TYÇ, TR-NQF-HE, EQF-LLL, ISCED (2011):Level 7 QF-EHEA:Second Cycle TR-NQF-HE, ISCED (1997-2013): 42,44

Ders Genel Tanıtım Bilgileri

Course Code:

3015002031

Ders İsmi:

Advanced Molecular Genetics

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Labs	Credit	ECTS
3	0	0	3	7

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Other Recommended Topics for the Course:

Type of course:

Anabilim Dalı/Lisansüstü Seçmeli

Course Level:

Master

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi Öykü İRİGÜL SÖNMEZ

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:	The aim of the course is to teach structure and function of the nucleic acids and proteins, DNA replication and repair mechanisms.
Course Content:	Structure and function of DNA and RNA, Dynamic three dimensional structure of prokaryotic and eukaryotic DNA, DNA replication, DNA repair mechanisms, protein structure and function.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Students will learn the structure and chemistry of DNA and RNA relate to their functions.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) Students will be able to explain relative stability of DNA and RNA, and their interactions with proteins.
Field Specific Competence
1) Students will know the complete structures of DNA components, the different forms of DNA (A, B, Z) and the types of amino acids that mediate backbone and sequence-specific binding.
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)
1)	Nucleic Acids: DNA a structure and functions	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2002
2)	Nücleic Acids: RNA structure and functions	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2003
3)	Dynamic 3-D structure of prokaryotic DNA	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2004
4)	Dynamic 3-D structure of chromosomes	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2005
5)	Gene Structure	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2006
6)	Content of the Genome	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2007
7)	Biochemical foundations of DNA replication in prokaryotes and discovering researches.	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2008
8)	Midterm
9)	Biochemical foundations of DNA replication in eukaryotes and discovering researches.	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2008
10)	DNA Recombination	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2009
11)	DNA Repair	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2010
12)	Transposable elements and Retroviruses	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2011
13)	Protein structure and functions: Structure of amino acids and their groups Primary structure of proteins: polypeptides	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2012
14)	Secondary ( α heliks, β sheet )Tertiary and Quaternary structure of proteins	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2013
15)	Recent Literature Discussion	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2014
16)

Sources

Course Notes / Textbooks:	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2002
References:	Molecular Biology of the Cell, 4th edition Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter Garland Science 2002

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3
Program Outcomes
1) Possessing sufficient knowledge required in the field of Molecular Biology and Genetics.
2) Being able to use the theoretical knowledge required in the field of Molecular Biology and Genetics.
3) Being able to apply practical skills required in the field of Molecular Biology and Genetics.
4) Being able to identify, define, and interpret problems in the field of Molecular Biology and Genetics.
5) Being able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
6) Being able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
7) Being able to understand and interpret any process, event, phenomenon, equipment, or product.
8) Being able to solve encountered problems using appropriate and modern methods.
9) Being able to show interest in different disciplines outside the field for personal and professional development.
10) Being able to select and use modern tools required for Molecular Biology and Genetics applications.
11) Being able to effectively use information technologies for Molecular Biology and Genetics applications.
12) Being able to design, conduct experiments, collect data, analyze results, report, archive, decode and/or interpret in the field of Molecular Biology and Genetics.
13) Being able to take responsibility, solve unexpected complex situations, and communicate well both individually and as a team member in applications of Molecular Biology and Genetics.
14) Being able to effectively communicate in Turkish, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
15) Being able to effectively communicate in at least one foreign language, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
16) Possessing the awareness of the necessity of lifelong learning, the ability to access information, follow developments in science and technology, and constantly renew oneself.
17) Possessing the awareness of societal, scientific, and ethical values in the collection, interpretation, dissemination, and application of data related to the field of Molecular Biology and Genetics and the consciousness to protect these values.
18) Being able to understand the universal and societal impacts (environmental issues, economy, sustainability, etc.) and legal aspects of Molecular Biology and Genetics applications.

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Possessing sufficient knowledge required in the field of Molecular Biology and Genetics.
2)	Being able to use the theoretical knowledge required in the field of Molecular Biology and Genetics.
3)	Being able to apply practical skills required in the field of Molecular Biology and Genetics.
4)	Being able to identify, define, and interpret problems in the field of Molecular Biology and Genetics.
5)	Being able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
6)	Being able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
7)	Being able to understand and interpret any process, event, phenomenon, equipment, or product.
8)	Being able to solve encountered problems using appropriate and modern methods.
9)	Being able to show interest in different disciplines outside the field for personal and professional development.
10)	Being able to select and use modern tools required for Molecular Biology and Genetics applications.
11)	Being able to effectively use information technologies for Molecular Biology and Genetics applications.
12)	Being able to design, conduct experiments, collect data, analyze results, report, archive, decode and/or interpret in the field of Molecular Biology and Genetics.
13)	Being able to take responsibility, solve unexpected complex situations, and communicate well both individually and as a team member in applications of Molecular Biology and Genetics.
14)	Being able to effectively communicate in Turkish, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
15)	Being able to effectively communicate in at least one foreign language, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
16)	Possessing the awareness of the necessity of lifelong learning, the ability to access information, follow developments in science and technology, and constantly renew oneself.
17)	Possessing the awareness of societal, scientific, and ethical values in the collection, interpretation, dissemination, and application of data related to the field of Molecular Biology and Genetics and the consciousness to protect these values.
18)	Being able to understand the universal and societal impacts (environmental issues, economy, sustainability, etc.) and legal aspects of Molecular Biology and Genetics applications.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Alan Çalışması
Anlatım
Course
Okuma

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Sözlü sınav
Homework
Bireysel Proje

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	15	% 20
Midterms	1	% 30
Semester Final Exam	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	15	2	30
Study Hours Out of Class	15	5	75
Presentations / Seminar	15	2	30
Homework Assignments	15	3	45
Quizzes	15	2	30
Midterms	1	2	2
Final	1	3	3
Total Workload			215