MOLECULAR BIOLOGY AND GENETICS (MASTER) (WHIT THESIS)
Master	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Ders Genel Tanıtım Bilgileri

Course Code:

3015002029

Ders İsmi:

Advanced Molecular Cell Biology

Ders Yarıyılı:

Fall

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
3	0	3	7

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Anabilim Dalı/Lisansüstü Seçmeli

Course Level:

Master

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:

The aim of the course is to give students detailed information on the structure and function of the genetic material and proteins, DNA replication and repair mechanisms, transcription and translation

Course Content:

Introduction, Structure and functions of Nucleic Acids: Nucleotides, Different Forms of DNA, structure of Chromosomes, DNA replication, DNA Repair, Structure and Functions of Proteins, Amino Acids, Polypeptides, Primary, Secondary, Tertiary, Quaternary structures of Proteins, Types of Proteins, Transcription, RNA splicing, Genetic Kod, Translation, Posttranslational Modifications, Experimental Methods used in Molecular Biology

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Students should be able to explain how the structure and chemistry of DNA and RNA relate to their functions, their relative stability, and their interactions with proteins.
2 - Skills
Cognitive - Practical
1) Students should be able to know the complete structures of DNA components, the different forms of DNA (A, B, Z) and relate DNA structure to forms of DNA damage.
3 - Competences
Communication and Social Competence
Learning Competence
1) Students should be able to compare & contrast mechanisms of DNA replication, repair, recombination.
Field Specific Competence
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	Introduction	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
2)	Structure and functions of Nucleic Acids: Nucleotides	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
3)	Structure and Functions of Nucleic Acids: DNA structure, Different Forms of DNA	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
4)	RNA Structure and Forms	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
5)	Content of the Genome and gene structure	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
6)	Chromatin and Chromosomal Structure	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
7)	DNA replication	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
8)	Midterm
9)	DNA Recombination and Repair	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
10)	Structure and Functions of Proteins, Amino Acids, Polypeptides, Primary, Secondary, Tertiary, Quaternary structures of Proteins Protein çeşitleri / Types of Proteins	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
11)	Transcription in Prokaryotes	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
12)	Transcription in Eukaryotes	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
13)	RNA Splicing and Modifications	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
14)	Genetic code and translation	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
15)	Recent Literature Discussion
16)	Final exam

Sources

Course Notes / Textbooks:	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.
References:	Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Science, Sinauer Associates Inc, Sunderland, 2002.

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3
Program Outcomes
1) Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2) Use of advanced theoretical and practical knowledge within the field.
3) Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
4) Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field.
5) Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data.
6) Organize and implement project and activities for social environment with a sense of social responsibility.
7) Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level.
8) Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge.
9) Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach.
10) Determine learning needs and direct the learning.
11) Develop positive attitude towards lifelong learning.
12) Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field.
13) Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
14) Conduct studies at an advanced level in the field independently.
15) Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field.
16) Planning and managing activities towards the development of subordinates in the framework of a project.

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2)	Use of advanced theoretical and practical knowledge within the field.
3)	Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
4)	Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field.
5)	Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data.
6)	Organize and implement project and activities for social environment with a sense of social responsibility.
7)	Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level.
8)	Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge.
9)	Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach.
10)	Determine learning needs and direct the learning.
11)	Develop positive attitude towards lifelong learning.
12)	Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field.
13)	Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
14)	Conduct studies at an advanced level in the field independently.
15)	Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field.
16)	Planning and managing activities towards the development of subordinates in the framework of a project.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Alan Çalışması
Anlatım
Course
Labs

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Homework
Bireysel Proje

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	15	% 20
Midterms	1	% 30
Semester Final Exam	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	15	2	30
Study Hours Out of Class	15	5	75
Presentations / Seminar	5	2	10
Project	5	5	25
Homework Assignments	15	2	30
Quizzes	15	2	30
Midterms	1	2	2
Final	1	3	3
Total Workload			205