DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS (ENGLISH)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Ders Genel Tanıtım Bilgileri

Course Code:

1414002046

Ders İsmi:

Population Genetics

Ders Yarıyılı:

Fall

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
2	2	3	5

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Department Elective

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:

The aim of the course is to provide the students with compherensive knowledge about the principles of population genetics and its applications

Course Content:

Introduction: Consepts used in Population Genetics, Genotype Frequencies: Hardy Weinberg Law and Applications Fixation Index and Heterozygosity, Gametic Disequlibrium, Genetic Drift and Effective Population Size, Population Structure and Gene Flow,Mutations ,Natural Selection, Models Molecular Evolution, Quantitative Trait Variation and Evolution, Mendelian basis of Quantitative Trait Variation, Application of Population Genetics.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) On completion of the lecture the students will have an extended knowledge of the genetic structure and dynamics of populations, and more understanding of the Hardy-Weinberg concept.
2 - Skills
Cognitive - Practical
1) Students will understand factors that contributes to genetic change and affects genetic equilibrium within a population, mutation, migration, selection and population size.
3 - Competences
Communication and Social Competence
Learning Competence
1) Students will know the concept of linkage disequilibrium in populations.
Field Specific Competence
1) Students will perform statistical analyses of population genetic and phylogenetic data
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	Introduction: Consepts used in Population Genetics	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-770
2)	Genotype Frequencies: Hardy Weinberg Law and Applications,	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-770
3)	Genotype Frequencies: Fixation Index and Heterozygosity, Gametic Disequlibrium	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-771
4)	Genetic Drift and Effective Population Size	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-773
5)	Genetic Drift and Effective Population Size	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-773
6)	Population Structure and Gene Flow	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-776
7)	Population Structure and Gene Flow	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-776
8)	Midterm exam
9)	Mutations	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-778
10)	Natural Selection	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-779
11)	Natural Selection Models	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-780
12)	Molecular Evolution	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-781
13)	Quantitative Trait Variation and Evolution	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-782
14)	Mendelian basis of Quantitative Trait Variation	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-783
15)	Semester subject review
16)	Final exam

Sources

Course Notes / Textbooks:	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-770
References:	Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK. ISBN 978-1405-132-770

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3	4
Program Outcomes
1) PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2) PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3) PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4) PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5) PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6) PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7) PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8) PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9) PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10) PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11) PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12) PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13) PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14) PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15) PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16) PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17) PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18) PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2)	PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3)	PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4)	PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5)	PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6)	PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7)	PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8)	PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9)	PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10)	PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11)	PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12)	PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13)	PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14)	PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15)	PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16)	PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17)	PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18)	PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Öğrenme Etkinliği ve Öğretme Yöntemleri

Alan Çalışması
Anlatım
Course
Homework

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Homework
Uygulama
Grup Projesi
Raporlama

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Application	15	% 20
Homework Assignments	7	% 0
Midterms	1	% 30
Semester Final Exam	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	15	2	30
Application	15	2	30
Study Hours Out of Class	15	4	60
Homework Assignments	15	2	30
Midterms	1	2	2
Final	1	2	2
Total Workload			154