MOLECULAR BIOLOGY AND GENETICS (MASTER) (WHIT THESIS)
Qualification Awarded	Program Süresi	Toplam Kredi (AKTS)	Öğretim Şekli	Yeterliliğin Düzeyi ve Öğrenme Alanı
Master's ( Second Cycle) Degree	2	120	FULL TIME	TYÇ, TR-NQF-HE, EQF-LLL, ISCED (2011):Level 7 QF-EHEA:Second Cycle TR-NQF-HE, ISCED (1997-2013): 42,44

Ders Genel Tanıtım Bilgileri

Course Code:

3015002011

Ders İsmi:

Pharmacogenetics

Ders Yarıyılı:

Fall

Ders Kredileri:

Theoretical	Practical	Labs	Credit	ECTS
3	0	0	3	6

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Other Recommended Topics for the Course:

Type of course:

Anabilim Dalı/Lisansüstü Seçmeli

Course Level:

Master

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:	Pharmacogenetics is the disipline of inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects.. Purpose of this course is to learn common introduction concerning pharmacogenetics and to learn concerning differential follow in drug effects.
Course Content:	In this course, pharmacokinetics, and pharmacodynamics affected by genetic factors, to evaluate and identify genetic characteristics changing effects of the drugs used for treatment and diagnosis, to have information about pharmacogenetics of drug transporters, and to transfer the knowledge obtained in this course in a systematic way

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) In this course, pharmacokinetics, and pharmacodynamics affected by genetic factors, to evaluate and identify genetic characteristics changing effects of the drugs used for treatment and diagnosis, to have information about pharmacogenetics of drug transporters, and to transfer the knowledge obtained in this course in a systematic way
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) In this course, pharmacokinetics, and pharmacodynamics affected by genetic factors, to evaluate and identify genetic characteristics changing effects of the drugs used for treatment and diagnosis, to have information about pharmacogenetics of drug transporters, and to transfer the knowledge obtained in this course in a systematic way
Field Specific Competence
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	General information	Textbook and Lecture notes
2)	Similarities and differences between pharmacogenetic and pharmacogenomic concepts	Textbook and Lecture notes
3)	Personalized treatments and pharmacogenetics	Textbook and Lecture notes
4)	Genetic polymorphism	Textbook and Lecture notes
5)	Genetic variations of Phase I enzymes	Textbook and Lecture notes
6)	Genetic variations of Phase II enzymes	Textbook and Lecture notes
7)	Case presentations on pharmacogenetics of drug transport molecules and its effect on drugs	Textbook and Lecture notes
8)	Midterm
9)	Pharmacogenetics of drug transporters I	Textbook and Lecture notes
10)	Pharmacogenetics of drug transporters II	Textbook and Lecture notes
11)	Pharmacogenetics of drug transporters III	Textbook and Lecture notes
12)	Case presentations on pharmacogenetics of drug transport molecules	Textbook and Lecture notes
13)	Changes in drug pharmacodynamics due to genetic factors	Textbook and Lecture notes
14)	Çevresel faktörlere ve beslenme alışkanlıklarına bağlı olarak enzim indüksiyon veya inhibisyonunda polimorfizmin etkisi	Textbook and Lecture notes
15)	Final exam

Sources

Course Notes / Textbooks:	Rang and Dale s Pharmacology, 7th. Edition Toksikoloji Ankara Üniversitesi Yayınları
References:	Rang and Dale s Pharmacology, 7th. Edition Toksikoloji Ankara Üniversitesi Yayınları

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2
Program Outcomes
1) Possessing sufficient knowledge required in the field of Molecular Biology and Genetics.
2) Being able to use the theoretical knowledge required in the field of Molecular Biology and Genetics.
3) Being able to apply practical skills required in the field of Molecular Biology and Genetics.
4) Being able to identify, define, and interpret problems in the field of Molecular Biology and Genetics.
5) Being able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
6) Being able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
7) Being able to understand and interpret any process, event, phenomenon, equipment, or product.
8) Being able to solve encountered problems using appropriate and modern methods.
9) Being able to show interest in different disciplines outside the field for personal and professional development.
10) Being able to select and use modern tools required for Molecular Biology and Genetics applications.
11) Being able to effectively use information technologies for Molecular Biology and Genetics applications.
12) Being able to design, conduct experiments, collect data, analyze results, report, archive, decode and/or interpret in the field of Molecular Biology and Genetics.
13) Being able to take responsibility, solve unexpected complex situations, and communicate well both individually and as a team member in applications of Molecular Biology and Genetics.
14) Being able to effectively communicate in Turkish, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
15) Being able to effectively communicate in at least one foreign language, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
16) Possessing the awareness of the necessity of lifelong learning, the ability to access information, follow developments in science and technology, and constantly renew oneself.
17) Possessing the awareness of societal, scientific, and ethical values in the collection, interpretation, dissemination, and application of data related to the field of Molecular Biology and Genetics and the consciousness to protect these values.
18) Being able to understand the universal and societal impacts (environmental issues, economy, sustainability, etc.) and legal aspects of Molecular Biology and Genetics applications.

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Possessing sufficient knowledge required in the field of Molecular Biology and Genetics.
2)	Being able to use the theoretical knowledge required in the field of Molecular Biology and Genetics.
3)	Being able to apply practical skills required in the field of Molecular Biology and Genetics.
4)	Being able to identify, define, and interpret problems in the field of Molecular Biology and Genetics.
5)	Being able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
6)	Being able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
7)	Being able to understand and interpret any process, event, phenomenon, equipment, or product.
8)	Being able to solve encountered problems using appropriate and modern methods.
9)	Being able to show interest in different disciplines outside the field for personal and professional development.
10)	Being able to select and use modern tools required for Molecular Biology and Genetics applications.
11)	Being able to effectively use information technologies for Molecular Biology and Genetics applications.
12)	Being able to design, conduct experiments, collect data, analyze results, report, archive, decode and/or interpret in the field of Molecular Biology and Genetics.
13)	Being able to take responsibility, solve unexpected complex situations, and communicate well both individually and as a team member in applications of Molecular Biology and Genetics.
14)	Being able to effectively communicate in Turkish, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
15)	Being able to effectively communicate in at least one foreign language, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
16)	Possessing the awareness of the necessity of lifelong learning, the ability to access information, follow developments in science and technology, and constantly renew oneself.
17)	Possessing the awareness of societal, scientific, and ethical values in the collection, interpretation, dissemination, and application of data related to the field of Molecular Biology and Genetics and the consciousness to protect these values.
18)	Being able to understand the universal and societal impacts (environmental issues, economy, sustainability, etc.) and legal aspects of Molecular Biology and Genetics applications.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Alan Çalışması
Anlatım
Course
Homework

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Sözlü sınav
Homework
Uygulama
Gözlem
Grup Projesi
Sunum

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	7	% 10
Midterms	1	% 30
Semester Final Exam	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	15	3	45
Study Hours Out of Class	15	5	75
Homework Assignments	10	4	40
Midterms	1	3	3
Final	1	3	3
Total Workload			166