MOLECULAR BIOLOGY AND GENETICS (MASTER) (WHIT THESIS) | |||||
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Qualification Awarded | Program Süresi | Toplam Kredi (AKTS) | Öğretim Şekli | Yeterliliğin Düzeyi ve Öğrenme Alanı | |
Master's ( Second Cycle) Degree | 2 | 120 | FULL TIME |
TYÇ, TR-NQF-HE, EQF-LLL, ISCED (2011):Level 7 QF-EHEA:Second Cycle TR-NQF-HE, ISCED (1997-2013): 42,44 |
Course Code: | 3015002011 | ||||||||||
Ders İsmi: | Pharmacogenetics | ||||||||||
Ders Yarıyılı: | Fall | ||||||||||
Ders Kredileri: |
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Language of instruction: | TR | ||||||||||
Ders Koşulu: | |||||||||||
Ders İş Deneyimini Gerektiriyor mu?: | No | ||||||||||
Other Recommended Topics for the Course: | |||||||||||
Type of course: | Anabilim Dalı/Lisansüstü Seçmeli | ||||||||||
Course Level: |
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Mode of Delivery: | Face to face | ||||||||||
Course Coordinator : | Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU | ||||||||||
Course Lecturer(s): | |||||||||||
Course Assistants: |
Course Objectives: | Pharmacogenetics is the disipline of inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects.. Purpose of this course is to learn common introduction concerning pharmacogenetics and to learn concerning differential follow in drug effects. |
Course Content: | In this course, pharmacokinetics, and pharmacodynamics affected by genetic factors, to evaluate and identify genetic characteristics changing effects of the drugs used for treatment and diagnosis, to have information about pharmacogenetics of drug transporters, and to transfer the knowledge obtained in this course in a systematic way |
The students who have succeeded in this course;
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Week | Subject | Related Preparation |
1) | General information | Textbook and Lecture notes |
2) | Similarities and differences between pharmacogenetic and pharmacogenomic concepts | Textbook and Lecture notes |
3) | Personalized treatments and pharmacogenetics | Textbook and Lecture notes |
4) | Genetic polymorphism | Textbook and Lecture notes |
5) | Genetic variations of Phase I enzymes | Textbook and Lecture notes |
6) | Genetic variations of Phase II enzymes | Textbook and Lecture notes |
7) | Case presentations on pharmacogenetics of drug transport molecules and its effect on drugs | Textbook and Lecture notes |
8) | Midterm | |
9) | Pharmacogenetics of drug transporters I | Textbook and Lecture notes |
10) | Pharmacogenetics of drug transporters II | Textbook and Lecture notes |
11) | Pharmacogenetics of drug transporters III | Textbook and Lecture notes |
12) | Case presentations on pharmacogenetics of drug transport molecules | Textbook and Lecture notes |
13) | Changes in drug pharmacodynamics due to genetic factors | Textbook and Lecture notes |
14) | Çevresel faktörlere ve beslenme alışkanlıklarına bağlı olarak enzim indüksiyon veya inhibisyonunda polimorfizmin etkisi | Textbook and Lecture notes |
15) | Final exam |
Course Notes / Textbooks: | Rang and Dale s Pharmacology, 7th. Edition Toksikoloji Ankara Üniversitesi Yayınları |
References: | Rang and Dale s Pharmacology, 7th. Edition Toksikoloji Ankara Üniversitesi Yayınları |
Ders Öğrenme Kazanımları | 1 |
2 |
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Program Outcomes | |||||||||||||||
1) Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources. | |||||||||||||||
2) Use of advanced theoretical and practical knowledge within the field. | |||||||||||||||
3) Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field. | |||||||||||||||
4) Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field. | |||||||||||||||
5) Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data. | |||||||||||||||
6) Organize and implement project and activities for social environment with a sense of social responsibility. | |||||||||||||||
7) Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level. | |||||||||||||||
8) Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge. | |||||||||||||||
9) Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach. | |||||||||||||||
10) Determine learning needs and direct the learning. | |||||||||||||||
11) Develop positive attitude towards lifelong learning. | |||||||||||||||
12) Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field. | |||||||||||||||
13) Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security. | |||||||||||||||
14) Conduct studies at an advanced level in the field independently. | |||||||||||||||
15) Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field. | |||||||||||||||
16) Planning and managing activities towards the development of subordinates in the framework of a project. |
No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
Program Outcomes | Level of Contribution | |
1) | Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources. | |
2) | Use of advanced theoretical and practical knowledge within the field. | |
3) | Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field. | |
4) | Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field. | |
5) | Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data. | |
6) | Organize and implement project and activities for social environment with a sense of social responsibility. | |
7) | Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level. | |
8) | Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge. | |
9) | Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach. | |
10) | Determine learning needs and direct the learning. | |
11) | Develop positive attitude towards lifelong learning. | |
12) | Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field. | |
13) | Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security. | |
14) | Conduct studies at an advanced level in the field independently. | |
15) | Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field. | |
16) | Planning and managing activities towards the development of subordinates in the framework of a project. |
Alan Çalışması | |
Anlatım | |
Course | |
Homework |
Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama) | |
Sözlü sınav | |
Homework | |
Uygulama | |
Gözlem | |
Grup Projesi | |
Sunum |
Semester Requirements | Number of Activities | Level of Contribution |
Homework Assignments | 7 | % 10 |
Midterms | 1 | % 30 |
Semester Final Exam | 1 | % 60 |
total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 40 | |
PERCENTAGE OF FINAL WORK | % 60 | |
total | % 100 |
Activities | Number of Activities | Duration (Hours) | Workload |
Course Hours | 15 | 3 | 45 |
Study Hours Out of Class | 15 | 5 | 75 |
Homework Assignments | 10 | 4 | 40 |
Midterms | 1 | 3 | 3 |
Final | 1 | 3 | 3 |
Total Workload | 166 |