MOLECULAR BIOLOGY AND GENETICS (MASTER) (WHIT THESIS)
Qualification Awarded Program Süresi Toplam Kredi (AKTS) Öğretim Şekli Yeterliliğin Düzeyi ve Öğrenme Alanı
2 120 FULL TIME TYÇ, TR-NQF-HE, EQF-LLL, ISCED (2011):Level 7
QF-EHEA:Second Cycle
TR-NQF-HE, ISCED (1997-2013): 42,44

Ders Genel Tanıtım Bilgileri

Course Code: 3015002006
Ders İsmi: Gene Therapy
Ders Yarıyılı: Spring
Ders Kredileri:
Theoretical Practical Labs Credit ECTS
3 0 0 3 6
Language of instruction: TR
Ders Koşulu:
Ders İş Deneyimini Gerektiriyor mu?: No
Other Recommended Topics for the Course:
Type of course: Anabilim Dalı/Lisansüstü Seçmeli
Course Level:
Master TR-NQF-HE:7. Master`s Degree QF-EHEA:Second Cycle EQF-LLL:7. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU
Course Lecturer(s):
Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives: Aim of this Course is to familiarize students with the most frequently used methods in Recombinant DNA Technology and Genetic Engineering from both a theoretical and experimental point of view.
Course Content: Recombinant DNA Technology and Genetic Engineering and Their Applications, DNA Restiction Enzymes, Cloning and Expression Vectors used for cloning, Gel Elecrophoresis of DNA and Proteins and Hybridization Techniques, Gene Transfer Techniques, DNA Sequence Analysis, Polymerase Chain Reaction, Construction and Use of Genomic and cDNA Libraries, Production of Recombinant Proteins, Production of Vaccines and Hormones in Microorganisms, Transgenic Plants and their Applications, Transgenic Animals and their applications, Impacts of Recombinant DNA and Genetic Engineering

Learning Outcomes

The students who have succeeded in this course;
Learning Outcomes
1 - Knowledge
Theoretical - Conceptual
1) Students learn basic methods of gene cloning and manipulation.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
1) Students have an extended knowledge on vaccine and hormon production and transgenic plants.
2) Students can discuss the impacts of the recombinant DNA technology.
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week Subject Related Preparation
1) Recombinant DNA Technology and Genetic Engineering and Their Applications Textbook and Lecture notes
2) DNA Restiction Enzymes Textbook and Lecture notes
3) Cloning and Expression Vectors Textbook and Lecture notes
4) Gel Elecrophoresis of DNA and Proteins and Hybridization Techniques Textbook and Lecture notes
5) Gene Transfer Techniques Textbook and Lecture notes
6) DNA Sequence Analysis Textbook and Lecture notes
7) Polymerase Chain Reaction Textbook and Lecture notes
8) Midterm
9) Construction and Use of Genomic and cDNA Libraries Textbook and Lecture notes
10) Manipulating DNA in Microorganisms other than E. coli Textbook and Lecture notes
11) Recombinant Protein Production Textbook and Lecture notes
12) Production of Vaccines and Hormones in Microorganisms Textbook and Lecture notes
13) Transgenic Animals and their Applications Textbook and Lecture notes
14) Transgenic Animals and their Applications Textbook and Lecture notes
15) Final

Sources

Course Notes / Textbooks: Principles of Gene Manipulation Sandy B., Primrose, Richard M. Twyman, Madlen, MA; Oxford: Blackwell Pub., (2006)
Gene Cloning and DNA Analysis An Introduction Fourth Edition T.A Brown
References: Principles of Gene Manipulation Sandy B., Primrose, Richard M. Twyman, Madlen, MA; Oxford: Blackwell Pub., (2006)
Gene Cloning and DNA Analysis An Introduction Fourth Edition T.A Brown

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları

1

2

3

Program Outcomes
1) Possessing sufficient knowledge required in the field of Molecular Biology and Genetics.
2) Being able to use the theoretical knowledge required in the field of Molecular Biology and Genetics.
3) Being able to apply practical skills required in the field of Molecular Biology and Genetics.
4) Being able to identify, define, and interpret problems in the field of Molecular Biology and Genetics.
5) Being able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
6) Being able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
7) Being able to understand and interpret any process, event, phenomenon, equipment, or product.
8) Being able to solve encountered problems using appropriate and modern methods.
9) Being able to show interest in different disciplines outside the field for personal and professional development.
10) Being able to select and use modern tools required for Molecular Biology and Genetics applications.
11) Being able to effectively use information technologies for Molecular Biology and Genetics applications.
12) Being able to design, conduct experiments, collect data, analyze results, report, archive, decode and/or interpret in the field of Molecular Biology and Genetics.
13) Being able to take responsibility, solve unexpected complex situations, and communicate well both individually and as a team member in applications of Molecular Biology and Genetics.
14) Being able to effectively communicate in Turkish, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
15) Being able to effectively communicate in at least one foreign language, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
16) Possessing the awareness of the necessity of lifelong learning, the ability to access information, follow developments in science and technology, and constantly renew oneself.
17) Possessing the awareness of societal, scientific, and ethical values in the collection, interpretation, dissemination, and application of data related to the field of Molecular Biology and Genetics and the consciousness to protect these values.
18) Being able to understand the universal and societal impacts (environmental issues, economy, sustainability, etc.) and legal aspects of Molecular Biology and Genetics applications.

Ders - Öğrenme Kazanımı İlişkisi

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Possessing sufficient knowledge required in the field of Molecular Biology and Genetics.
2) Being able to use the theoretical knowledge required in the field of Molecular Biology and Genetics.
3) Being able to apply practical skills required in the field of Molecular Biology and Genetics.
4) Being able to identify, define, and interpret problems in the field of Molecular Biology and Genetics.
5) Being able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
6) Being able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics.
7) Being able to understand and interpret any process, event, phenomenon, equipment, or product.
8) Being able to solve encountered problems using appropriate and modern methods.
9) Being able to show interest in different disciplines outside the field for personal and professional development.
10) Being able to select and use modern tools required for Molecular Biology and Genetics applications.
11) Being able to effectively use information technologies for Molecular Biology and Genetics applications.
12) Being able to design, conduct experiments, collect data, analyze results, report, archive, decode and/or interpret in the field of Molecular Biology and Genetics.
13) Being able to take responsibility, solve unexpected complex situations, and communicate well both individually and as a team member in applications of Molecular Biology and Genetics.
14) Being able to effectively communicate in Turkish, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
15) Being able to effectively communicate in at least one foreign language, both orally and in writing, to plan and carry out academic studies independently or with stakeholders in the field of Molecular Biology and Genetics.
16) Possessing the awareness of the necessity of lifelong learning, the ability to access information, follow developments in science and technology, and constantly renew oneself.
17) Possessing the awareness of societal, scientific, and ethical values in the collection, interpretation, dissemination, and application of data related to the field of Molecular Biology and Genetics and the consciousness to protect these values.
18) Being able to understand the universal and societal impacts (environmental issues, economy, sustainability, etc.) and legal aspects of Molecular Biology and Genetics applications.

Öğrenme Etkinliği ve Öğretme Yöntemleri

Alan Çalışması
Anlatım
Course
Homework

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Sözlü sınav
Homework
Sunum

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Homework Assignments 7 % 10
Midterms 1 % 30
Semester Final Exam 1 % 60
total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
total % 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities Number of Activities Duration (Hours) Workload
Course Hours 15 3 45
Study Hours Out of Class 15 5 75
Homework Assignments 10 4 40
Midterms 1 3 3
Final 1 3 3
Total Workload 166