DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS (ENGLISH)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Ders Genel Tanıtım Bilgileri

Course Code:

1414002041

Ders İsmi:

Clinical Genetics

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
2	2	3	5

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Department Elective

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:	Understanding the mechanisms that form the basis of heredity and genetic diseases.
Course Content:	Overview of genetical disaeases, Chromosome structure and organization, Mitochondrial DNA and diseases, Mendelian genetics, Non-Mendelian genetics,Epigenetics, Mutations and polymorphism, Cancer genetics, Hematological diseases and genetics, Immunogenetics, Human genetical diseases, Approachstrategies in genetic studies, Genetic counseling.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) By the end of the course the students will have detailed knowledge about the conventional and recent methods that are used in human genetics
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
1) By the end of the course the students will have detailed knowledge about genetic analyses and gene theraphy
Learning Competence
Field Specific Competence
1) By the end of the course the students will have detailed knowledge about using theoretical information for practical applications and ethical value
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	Preliminary preparations for human health tests.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
2)	Molecular diagnostic methods.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
2)	Molecular diagnostic methods.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
3)	Molecular diagnosis and methods in medical genetics.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
4)	Gene therapy.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
5)	Molecular approaches to genetic diseases.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
6)	Molecular approaches to genetic diseases.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
7)	Molecular approaches to genetic diseases.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
8)	Midterm
9)	New application fields in medical genetics.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
10)	The role of transgenic animals in medical genetic applications.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
11)	Proteomics and applications.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
12)	Stem cell therapy applications.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
13)	Personalized medicine.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
14)	Genetics and ethics.	New Clinical Genetics, Fourth Edition: A Guide to Genomic Medicine
15)	Semester subject review
16)	Final exam

Sources

Course Notes / Textbooks:	Fundamentals of Clinical Trials 5th ed. 2015 Edition
References:	Fundamentals of Clinical Trials 5th ed. 2015 Edition

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3
Program Outcomes
1) PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2) PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3) PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4) PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5) PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6) PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7) PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8) PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9) PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10) PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11) PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12) PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13) PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14) PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15) PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16) PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17) PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18) PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2)	PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3)	PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4)	PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5)	PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6)	PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7)	PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8)	PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9)	PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10)	PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11)	PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12)	PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13)	PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14)	PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15)	PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16)	PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17)	PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18)	PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Öğrenme Etkinliği ve Öğretme Yöntemleri

Anlatım
Course
Labs
Homework

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Homework
Uygulama
Gözlem
Grup Projesi

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Application	15	% 20
Midterms	1	% 30
Semester Final Exam	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	15	2	30
Application	15	2	30
Study Hours Out of Class	15	4	60
Homework Assignments	15	2	30
Midterms	1	2	2
Final	1	2	2
Total Workload			154