DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS (ENGLISH)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Ders Genel Tanıtım Bilgileri

Course Code:

1414002037

Ders İsmi:

Protein Structure and Function

Ders Yarıyılı:

Fall

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
2	2	3	5

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Department Elective

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi Hasan KAHRAMAN

Course Lecturer(s):

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:

The aim of course is: -To teach basic theoretical knowledge about Enzymology -To provide information about the Chemical Structure and Properties of Enzymes -
To explain the effect of Enzyme Catalyst -To teach Classification of Enzymes -To teach Non-enzymatic Biological Catalysis, -To explain The Enzymes in Drug
Design

Course Content:

Course Content : General Properties of Enzymes,Chemistry of Enzymes, Enzymes as the Catalyst, Enzymatic Reactions, Classification of Enzymes, Hydrolyticand Group Transfer Reactions, Enzymatic Redox Chemistry, Enzymatic Carbon-Carbon Bond Formation, Enzymatic Addition/Elimination Reactions, EnzymaticTransformations of Amino Acids, Isomerases, Non-enzymatic Biological Catalysis, Enzymes in Drug Design

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) the end of the course the students will have the ability to learn about basic theoretical knowledge of Enzymology.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) By the end of the course students will learn about Enzymes as the Catalyst.
Field Specific Competence
Competence to Work Independently and Take Responsibility
1) By the end of the course the students will have the ability to understand how enzymes work and how enzymatic reactions.

Ders Akış Planı

Week	Subject	Related Preparation
1)	General Properties of Enzymes	Proteins: Structure and Function
2)	Chemistry of Enzymes	Proteins: Structure and Function
3)	Enzymes as the Catalyst	Proteins: Structure and Function
4)	Enzymatic Reactions	Proteins: Structure and Function
5)	Classification of Enzymes	Proteins: Structure and Function
6)	Hydrolytic and Group Transfer Reactions	Proteins: Structure and Function
7)	Ezyme Isolation	Proteins: Structure and Function
8)	midterm
9)	Enzymatic Carbon-Carbon Bond Formation	Proteins: Structure and Function
10)	Enzyme Immobilization	Proteins: Structure and Function
11)	Industrial Enzymes	Proteins: Structure and Function
12)	Industrial Enzymes	Proteins: Structure and Function
13)	Fermentation systems	Proteins: Structure and Function
14)	Fermentation systems	Proteins: Structure and Function
15)	Final

Sources

Course Notes / Textbooks:	An Introduction to Enzyme and Coenzyme Chemistry, Tim Bugg, Blackwell Science Ltd. USA, 1997 Enzymes in Synthetic Organic Chemistry, C.H. Wong and G.M. Whitesides, Elsevier Science Ltd, U.K, 1995
References:	An Introduction to Enzyme and Coenzyme Chemistry, Tim Bugg, Blackwell Science Ltd. USA, 1997 Enzymes in Synthetic Organic Chemistry, C.H. Wong and G.M. Whitesides, Elsevier Science Ltd, U.K, 1995

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	2	3
Program Outcomes
1) PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2) PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3) PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4) PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5) PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6) PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7) PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8) PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9) PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10) PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11) PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12) PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13) PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14) PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15) PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16) PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17) PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18) PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2)	PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3)	PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4)	PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5)	PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6)	PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7)	PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8)	PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9)	PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10)	PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11)	PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12)	PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13)	PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14)	PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15)	PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16)	PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17)	PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18)	PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Öğrenme Etkinliği ve Öğretme Yöntemleri

Alan Çalışması
Anlatım
Course
Labs

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Homework
Bireysel Proje
Sunum

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Application	13	% 20
Midterms	1	% 30
Semester Final Exam	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	13	2	26
Application	13	2	26
Study Hours Out of Class	13	5	65
Quizzes	13	2	26
Midterms	1	2	2
Final	1	2	2
Total Workload			147