DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS (ENGLISH)
Qualification Awarded Program Süresi Toplam Kredi (AKTS) Öğretim Şekli Yeterliliğin Düzeyi ve Öğrenme Alanı
4 240 FULL TIME TYÇ, TR-NQF-HE, EQF-LLL, ISCED (2011):Level 6
QF-EHEA:First Cycle
TR-NQF-HE, ISCED (1997-2013): 42,44,52,62,72,85

Ders Genel Tanıtım Bilgileri

Course Code: 1414002022
Ders İsmi: Molecular Biology of Cancer
Ders Yarıyılı: Spring
Ders Kredileri:
Theoretical Practical Labs Credit ECTS
2 2 0 3 5
Language of instruction: EN
Ders Koşulu:
Ders İş Deneyimini Gerektiriyor mu?: No
Other Recommended Topics for the Course:
Type of course: Department Elective
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Prof. Dr. Meliha Burcu IRMAK YAZICIOĞLU
Course Lecturer(s):
Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives: This course aims to educate students on various genetic and molecular changes normal cells undergo during transformation into malignant cancer cells
Course Content: Introduction to cancer biology; DNA structure and stability: mutations versus repair; Regulation of gene expression; Growth factor signaling and oncogenes; Thecell cycle; Growth inhibition and tumor suppressor genes; Apoptosis; Stem cells and differentiation; Metastasis; The immune system, infections, and inflammation;Nutrients, hormones, and gene interactions; The cancer industry: drug development, pharmacogenomics, and clinical trial design; Cancer in the future

Learning Outcomes

The students who have succeeded in this course;
Learning Outcomes
1 - Knowledge
Theoretical - Conceptual
1) To give students a general perspective about cancer biology.
2 - Skills
Cognitive - Practical
1) To develop fundamental concepts of cancer identification, etiology and epidemiology.
3 - Competences
Communication and Social Competence
Learning Competence
1) To understand the cellular and molecular basis of current strategies for cancer prevention and treatment.
Field Specific Competence
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week Subject Related Preparation
1) Introduction to Cancer Biology Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
2) Tumor viruses Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
3) In vitro cancer cells Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
4) Cancer-related genes Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
5) Cancer-related genes-Growth factor receptors Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
6) Cancer-related genes -Tumor suppressor genes Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
7) Control of the cell cycle Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
8) Midterm
9) Control of the cell cycle and cancer Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
10) Stem cells and cancer Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
11) Apoptosis Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
12) Metastasis Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
13) Angiogenesis Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
14) Epigenetic mechanisms in cancer Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
15) RNA interference and cancer Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
16) Final exam

Sources

Course Notes / Textbooks: Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012
References: Molecular Biology of Cancer, L. Pecorino, Oxford University Press, 2012

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları

1

2

3
Program Outcomes
1) PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2) PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3) PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4) PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5) PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6) PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7) PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8) PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9) PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10) PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11) PO 5.2) To be able to use information technologies effectively for Molecular Biology and Genetics applications
12) PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13) PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14) PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15) PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16) PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17) PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18) PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Ders - Öğrenme Kazanımı İlişkisi

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2) PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3) PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4) PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5) PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6) PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7) PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8) PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9) PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10) PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11) PO 5.2) To be able to use information technologies effectively for Molecular Biology and Genetics applications
12) PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13) PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14) PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15) PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16) PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17) PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18) PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Öğrenme Etkinliği ve Öğretme Yöntemleri

Akran Değerlendirmesi
Anlatım
Course
Homework

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Sözlü sınav
Homework
Uygulama
Sunum
Akran Değerlendirmesi
Tez Sunma

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Application 15 % 20
Midterms 1 % 30
Semester Final Exam 1 % 50
total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
total % 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities Number of Activities Duration (Hours) Workload
Course Hours 15 2 30
Application 15 2 30
Study Hours Out of Class 15 4 60
Homework Assignments 15 2 30
Midterms 1 2 2
Final 1 2 2
Total Workload 154