DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS (ENGLISH)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Ders Genel Tanıtım Bilgileri

Course Code:

1414321002

Ders İsmi:

Biochemistry II

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
3	2	4	6

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Necessary

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi Erdem TEZCAN

Course Lecturer(s):

Dr.Öğr.Üyesi Erdem TEZCAN

Course Assistants:

Dersin Amaç ve İçeriği

Course Objectives:	Understanding the synthesis and degradation metabolisms of biological molecules.
Course Content:	Energy and Metabolism, Formation of phosphate bond energy and Catabolism, Glycolysis, The Citric Acid Cycle, Oxidative Phosphorylation, Oxidation of Fatty Acids and Oxidative Degration of Amino-Acids, Photosynthesis, Biosynthesis of Carbohydrates, Lipids, Amino Acids and Nucleic Acids, Hormones and Vitamins

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Students will learn the principles of Bioenergetics.
2) Students will learn The Synthesis Reaction and Biodegration of Proteins.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) Students will learn The Synthesis Reaction and Biodegration of Lipids.
Field Specific Competence
1) Students will learn The Synthesis Reaction and Biodegration of Carbohydrates.
Competence to Work Independently and Take Responsibility

Ders Akış Planı

Week	Subject	Related Preparation
1)	General Principles of metabolism	Textbook and Lecture notes
2)	Glycolysis, gluconeogenesis and the pentose phosphate pathwork/Laboratory Introduction	Textbook and Lecture notes
3)	Glycolysis, gluconeogenesis and the pentose phosphate pathwork / Quantitative Ascorbic Acid (Vitamin C) Analysis	Textbook and Lecture notes
4)	Principles of Metabolic Regulation /Determination of Hemoglobin in Blood	Textbook and Lecture notes
4)	Principles of Metabolic Regulation /Determination of Hemoglobin in Blood	Textbook and Lecture notes
5)	The Citric Acid Cycle /Quantitative Determination of Catalase Activity in Kidney and Liver Tissues	Textbook and Lecture notes
6)	Regulation of carbohydrate metabolism / Lipid Determination	Textbook and Lecture notes
7)	Fatty acid catabolism / Determination of Glutathione Level	Textbook and Lecture notes
8)	Midterm
9)	Fatty acid catabolism / Determination of Nitric Oxide / Determination of Plasma Proteins	Textbook and Lecture notes
10)	Lipid Biosynthesis / Thin Layer Chromatography	Textbook and Lecture notes
11)	Cholesterol metabolism / SDS PAGE Gel Solution Preparation	Textbook and Lecture notes
12)	Lipoproteins / SDS PAGE Gel Preparation	Textbook and Lecture notes
13)	Lipid Biosynthesis / Compensation Experiment	Textbook and Lecture notes
14)	Biosynthesis of amino acids and nucleotides and related molecules / Compensation Experiment	Textbook and Lecture notes
15)	Final

Sources

Course Notes / Textbooks:	Lehninger: Biyokimyanın İlkeleri, Çeviri: Y. Murat Elçin Palme yayıncılık. Biyokimya, Jeremy M. Berg John L. Tymoczko Lubert Stryer, Palme Yayıncılık Lehninger Principles of Biochemistry, Albert L. Lehninger, David Lee Nelson,Michael M. Cox; W.H. Freeman, New York, 2008. Biochemistry, Jeremy M. Berg John L. Tymoczko Lubert Stryer. 2011
References:	Lehninger: Biyokimyanın İlkeleri, Çeviri: Y. Murat Elçin Palme yayıncılık. Biyokimya, Jeremy M. Berg John L. Tymoczko Lubert Stryer, Palme Yayıncılık Lehninger Principles of Biochemistry, Albert L. Lehninger, David Lee Nelson,Michael M. Cox; W.H. Freeman, New York, 2008. Biochemistry, Jeremy M. Berg John L. Tymoczko Lubert Stryer. 2011

Ders - Program Öğrenme Kazanım İlişkisi

Ders Öğrenme Kazanımları	1	4	2	3
Program Outcomes
1) PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics
2) PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics
3) PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field
4) PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5) PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
6) PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics
7) PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product
8) PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9) PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10) PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications
11) PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications
12) PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13) PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.
14) PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders
15) PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16) PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.
17) PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18) PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Ders - Öğrenme Kazanımı İlişkisi

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	PÇ 1.1) To have sufficient knowledge required by the field of molecular biology and genetics	4
2)	PO 1.2) To be able to use the theoretical knowledge required by the field of molecular biology and genetics	3
3)	PO 1.3) To be able to apply the skills required by the field of molecular biology and genetics in the field	4
4)	PO 2.1) To be able to identify, define and interpret the problems in the field of Molecular Biology and Genetics
5)	PO 2.2) To be able to select appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics	4
6)	PO 2.3) To be able to apply appropriate analysis and modeling methods to solve problems in the field of Molecular Biology and Genetics	3
7)	PO 3.1) To be able to understand and interpret any process, event, phenomenon, equipment or product	2
8)	PO 3.2) To be able to solve the problems encountered with appropriate and contemporary methods
9)	PO 4.) To be able to show interest in different disciplines outside the field for personal and professional development
10)	PO 5.1) To be able to select and use modern tools necessary for Molecular Biology and Genetics applications	3
11)	PO 5.2)To be able to use information technologies effectively for Molecular Biology and Genetics applications	5
12)	PO 6) To be able to design, experiment, field study, data collection, data analysis, reporting, archiving, text solving and/or interpretation in the field of Molecular Biology and Genetics
13)	PO 7) To be able to take responsibility as an individual and a team member, to produce solutions and to communicate well in unexpected complex situations that may be encountered in applications in the field of Molecular Biology and Genetics.	3
14)	PO 8.1) To be able to communicate effectively both orally and in writing in Turkish in order to plan academic studies in the field of Molecular Biology and Genetics and to carry out them independently or jointly with stakeholders	4
15)	PO 8.2) To be able to communicate orally and in writing in at least one foreign language in order to plan academic studies in the field of Molecular Biology and Genetics and to conduct them independently or jointly with stakeholders
16)	PO 9) To have the awareness of the necessity of lifelong learning, to have the ability to access information, to follow developments in science and technology and to have the ability to constantly renew oneself.	4
17)	PO 10) To have social, scientific, ethical values and awareness of protecting these values in the stages of collecting, interpreting, announcing and applying data related to the field of Molecular Biology and Genetics.
18)	PO 11) To be able to comprehend the universal and social effects of Molecular Biology and Genetics applications (environmental problems, economy, sustainability, etc.) and legal aspects

Öğrenme Etkinliği ve Öğretme Yöntemleri

Beyin fırtınası /Altı şapka
Course
Labs
Homework
Rapor Yazma

Ölçme ve Değerlendirme Yöntemleri ve Kriterleri

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Homework
Uygulama
Raporlama

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Laboratory	13	% 10
Midterms	1	% 30
Semester Final Exam	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

İş Yükü ve AKTS Kredisi Hesaplaması

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	13	4	52
Laboratory	13	2	26
Study Hours Out of Class	13	4	52
Homework Assignments	10	3	30
Quizzes	5	1	5
Total Workload			165